Yusuke Urameshi is a famous troublemaker in his junior high school. One day, he saves a little boy from a car accident, but he is run over by the car instead. However, it wasn't the end of his life. Yusuke is told if he completes missions from the Spiritual World, he would come back to his life! His task is to arrest the ghosts and demons that harm the human world.
As Yusuke starts to investigate, he gets help from his rival, Kuwabara, as well as Kurama and Hiei whom he has encountered on missions. Yusuke, often feeling frustrated and desperate, thrives in the series of battles to become the strongest fighter of all. Is Yusuke able to complete his mission to come back to his life?!